June 27, 2022

Press Release "Success in Development of New Technology for Highly Sensitive and Accurate Detection and Analysis of Trace Amounts of RNA at the Single Cell Level" (Paper published in Communications Biology, a sister journal of Nature.)

A paper by Assistant Professor Shigeyuki Shichino, Associate Professor Satoshi Ueha, and Professor Kouji Matsushima of the Division of Inflammation and Immunology, Institute of Biomedical Research and Innovation, Tokyo University of Science, and others on our original TAS-seq method has been published in Communications Biology, a sister journal of Nature.

TAS-seq was recognized as an analytical technology that surpasses existing technologies.

* We perform contracted scRNA-seq analysis using the above technology.

[Patent Pending] Owned by Tokyo University of Science and exclusively licensed by ImmunoGeneTeqs

Abstract and key points of the study

  • We have newly developed the TAS-Seq method, a single-cell RNA sequencing analysis method that can analyze minute amounts of RNA in a single cell with higher sensitivity and precision than existing technologies.

  • TAS-Seq has excellent sensitivity in detecting expressed genes and quantifying cellular composition, and can more reliably detect intercellular communication, which is difficult to detect with existing technologies.

  • By developing this research, more in vivo information can be obtained from a single cell, which is expected to contribute to the elucidation of the pathogenic mechanisms of various diseases and the advancement of drug discovery research.

Communications Biology article

TAS-Seq is a robust and sensitive amplification method for bead-based scRNA-seq | Communications Biology (nature.com)

Tokyo University of Science Press Release

Japanese: https://www.tus.ac.jp/today/archive/20220627_5628.html

English: https://www.tus.ac.jp/en/mediarelations/archive/20220627_5628.html

English video URL: https://youtu.be/B803lwsiu9w

AMED Press Release